Infrastructure

We manage a number of systems and services to make researchers more productive. Some of our systems and ways we can help are outlined below:

Cluster

The Life Sciences cluster consists of the following hardware:

14 nodes: Dual Intel® Xeon™ CPU 3.06GHz, 2GB RAM, RHEL3 U8 ×86
36 nodes: Dual Intel® Xeon™ CPU 2.80GHz, 4GB RAM, RHEL3 U8 ×86
14 nodes: Dual Intel® Xeon™ CPU 2.80GHz, 2GB RAM, RHEL3 U8 ×86
22 nodes: Dual Intel® Xeon™ CPU 2.80GHz, 2.5GB RAM, RHEL3 U8 ×86_64
12 nodes: Quad Intel® Xeon™ CPU 2.80GHz, 8GB RAM, RHEL4 U3 ×86_64
1 node: Quad Genuine Intel® CPU 3.00GHz, 8GB RAM, RHEL4 U4 ×86_64
1 node: Dual Core AMD Opteron™ Processor 275, 4GB RAM, x86_64
1 node: Intel® Xeon™ CPU 3.20GHz, 4GB RAM RHEL4 U4, x86_64
1 node: Dual Core Intel® Xeon™ CPU 2.40GHz, 1GB RAM, RHEL4 U4, x86
Total: 229 cpus

Cluster head node: portal.cgr.harvard.edu
Dual Intel® Xeon™ CPU 3.06GHz, 2GB RAM, RHEL3 U8 ×86

Cluster Network: 1Us with 1GB NIC, IBM Blades chassis with 4 trunked ports, DellBlades with 1GB pass-through all connected into a Foundry Networks FastIron 1500 switch. 10 DellBlades have Infiniband network as well as 1GB pass-through network.

Admin host: serving the cluster is a IBM Blade server running DHCP, LSF licenses, Mathematica licenses. It contains Dual Intel® Xeon™ CPU 3.00GHz, 4GB RAM, RHEL4 U4 ×86

Disk Storage: All Nodes mount a central EMC SAN (through NSXs) on the cluster network via NFS. Each node has local scratch space which varies from 13GB to 67GB.

Tape Backup Robot: ADIC Scalar i2000 - 600 tape unit.

Backup Infrastructure: EMC Networker v7.2.2 on Linux, NDMP clients are 6 EMC NSXs. All zoned into one Cisco Fiber switch. Sustained tape backup speeds of 110-140+ MB/s from one NSX to one LTO-3 tape drive.

Queuing System: LSF v6.0 from Platform Computing (www.platform.com)

Current queues defined:

QUEUE_NAME      PRIO STATUS          MAX JL/U JL/P JL/H NJOBS  PEND   RUN  SUSP
interact         86  Open:Active       -    1    -    -     0     0     0     0
dellblades       85  Open:Active       -    -    -    -   460   416    44     0
delllong         84  Open:Active       -    -    -    -     4     0     4     0
rsoft            83  Open:Active       -    2    -    -     0     0     0     0
hunter           82  Open:Active       -    -    -    -     0     0     0     0
giribet          81  Open:Active       -    -    -    -    80     0    80     0
flybase          70  Open:Active       -    -    -    -     0     0     0     0
blades           65  Open:Active       -    -    -    -     0     0     0     0
CGRshort         60  Open:Active       -   50    -    -     0     0     0     0
CGRnormal        50  Open:Active      40    -    -    -   460   420    40     0
CGRlong          40  Open:Active       -   60    -    -     0     0     0     0
short            30  Open:Active       -   20    -    -     0     0     0     0
normal           20  Open:Active       -    -    -    -  5285  5161   123     1
long             15  Open:Active       -   10    -    -    24     0    24     0
 

interact - for interactive jobs with a MAX of 12hrs runtime, 1 job per
user dellblades - for jobs to run on Dellblades1-10, primary group that uses these is the karplus group.


rsoft - for jobs from the Lieber lab to run rsoft based jobs, only run on host cfa15 for 12hrs MAX runtime.


hunter - for jobs from the hunter lab group to run on hunter1, they have priority access to this machine.
giribet - for jobs from the Giribet lab to run on giribet1-2. They have
exclusive access to these machines.
flybase - for jobs from the Flybase group, to run in hosts fb1-22. They have priority access to fb1-22.
CGRshort - for jobs from CGR members that have a MAX runtime of 1hr.
CGRnormal - for jobs form CGR members that have a MAX runtime of 24hrs. maximum of 40 jobs total at any one time.
CGRlong - for jobs from CGR members, no time limit. Maximum of 60 jobs per users at any one time.
short - for all external or CGR members that run jobs for a MAX of 1hr runtime. Total of 20 jobs per user.
normal - for all external or CGR members that run jobs for a MAX of 24hrs runtime.
long - for all external or CGR members, no time limit, 10 jobs MAX per user.

Desktop

:::Last Updated on 13NOV2006:::

Each new desktop assigned to a new Life Sciences individual will be an up-to-date desktop system with the following features:

  1. Pentium-4 @ > 3.2Ghz
  2. > 1.0gb RAM
  3. > 200gb Hard Drive
  4. > 17" LCD Display

The current desktops being issued are the Dell Optiplex GX620 and more information about them can be found here.

Additionally all Windows computers will come issued with the following software (in its most up-to-date version):

  1. Symantec Antivirus Corporate or McAfee Antivirus
  2. Microsoft Office with frontpage
  3. Adobe Acrobat Reader

Lastly, the desktop will be part of the domain and be subject to both antiviurs and Windows updates at regular intervals.

Email

Life Sciences Division Research Computing operates and maintains a Microsoft Exchange environment; this allows for integrated and collaborative email, address books, calendars, and more for all users with accounts. We support MAPI as well as POP, IMAP, and HTTP (WebMail) protocols. Email is scanned for SPAM and malware. Suspected SPAM is labeled “[Possible SPAM]”. Malware-infested email is not delivered. The default mailbox quota is 500MB. To get a Life Sciences email account, go to the Life Sciences Division (“LSDiv”) account request page and fill out the form.

Accessing another calendar using Entourage

Accessing Another Calendar using Entrouage

Configuring RPC over HTTP for Outlook

Configuring RPC over HTTP for Outlook

Email: Clients

The following Email clients are supported by the Division of Life Sciences. Outlook XP/2003/2007 Entourage Thunderbird Outlook Web Access (Webmail)

Moving Calendars from Meeting Maker to Exchange

Moving Calendars from Meeting Maker to Exchange

Software

 

This page has two sections: Desktop/Laptop Software and Cluster Software

Software for your Desktop or Laptop Computer

The following products are licensed by FAS and are available to FAS affiliates on CDs from the FAS Desktop Support team. Fill out a copy of the FAS Software Agreement form for each computer on which the software will be installed. Click http://www.fas.harvard.edu/~fascs/SoftAgreeForm.doc to download the form.

Software on CD:

OSX Windows
Microsoft Office 2004 Microsoft Office 2003
FileMaker Pro v. 8 FileMaker Pro v. 8
OS X v. 10.4 (Tiger) and 10.3 (Panther) Windows XP

FAS-Downloadable Software:

FAS offers a variety of downloadable software; access is by Pin Authentication.
The following list is both abbreviated and likely to be out of date; the current complete list is here: http://www.fas.harvard.edu/cgi-bin/software/download.pl?platform=all

  OSX Windows
AntiVirus Software Virex 7.7 VirusScan 8 Enterprise
Acrobat Professional v. 7.0.3 (keyed) v. 7 (keyed)
Dreamweaver v. 7.0.1 (keyed)
v. 2004 (keyed)
EndNote v. 9.0 (keyed) v. X (keyed)
Mathematica v. 5.2.2 v. 5.2
MatLab (requires VPN connection) v. 7.2 R2006a
Photoshop CS2 v. 9.0 (keyed) v. CS2 (keyed)
Statistical analysis

 

SPSS 13.0 (keyed)

Stata 9.0 (keyed)

MiniTab 14.2 (keyed)

SPSS 14.0 (keyed)

SPSS Smart Viewer 13.0 (keyed)

Stata Intercooled v. 9.0 (keyed)

VPN Client v. 4.9 v. 4.0.4

You’ll have to install the KeyServer Client to use FAS’s “keyed” software. Keyed software is free to users, but when all the keys are in use, additional users can’t run the software.

Downloadable Software:

MCB lecture and conference room schedules (and a couple of lab calendars) are hosted on the Life Sciences Meeting Maker server (request a Meeting Maker account by emailing support [-at-] lsdiv [dot] harvard [dot] edu). Please contact the HelpDesk at 6-2727 or email support [-at-] lsdiv [dot] harvard [dot] edu for help downloading and configuring the client software and connecting to the server.

  OSX Windows
MeetingMaker Client 7.5 7.5

WinZip

 

License # is in the ReadMe file

Other “Desktop” Software:

UIS SITE (http://www.uis.harvard.edu/enterprise_licensing/catalog/?searchby=vendor) has other products (including Adobe Creative Suite, Acrobat Professional and Photoshop). To browse the catalog and order from it, you’ll have to enter your Harvard ID and PIN. Licenses are sold separately from media. You’ll need one license for each computer the software will be installed on.

DNA Sequencing Software:

VectorNTI – Invitrogen continues to support the PC version of VectorNTI, and now offers it to educational users for free. Unfortunately, they are no longer updating the Macintosh version, though the most recent Mac version, 7.1, is still downloadable – note: this requires a bootable Panther (10.3.9) partition - contact FASCS for assistance with this (6-2727).

To get a free license to use the software, click the “Join Today” button on the VectorNTI User Community page; download the software from this page

Lasergene – Lasergene has been suggested as a replacement for VectorNTI for Mac users with Tiger. DNAStar offers a 15-day free Lasergene trial here.

Desktop Software Updates

Keep your OS and applications software updated to minimize the risk of being hacked. Here’s where to find these updates.

http://internal.mcb.harvard.edu/Tech/CompServices/ObtainSoftware/index.html#Updates

Software on the Bauer Core Linux Cluster

Applications running on the cluster are available to Harvard research groups. A few of the popular applications are:

* BLAST (NCBI and WU)

* EMBOSS

* Primer3

* QRNA and SNOSCAN

* Bioperl

* GMEP

* Mathematica (Bauer Lab only)

Access to the Cluster requires a Bauer Core account. Research groups may subscribe to the cluster by paying a nominal fee of $100 per month. More information is available at http://www.sysbio.harvard.edu/csb/resources/computational/linux.html

More information on Databases, Microarray analysis, Programming tools, Sequence analysis, and Visualization and modeling is available on the following web page: http://www.sysbio.harvard.edu/csb/resources/computational/resource.html

 

Storage

Storage...

User Accounts

Access to networked resources is granted through Domain User accounts. Life Sciences Division affiliates, once they have a Harvard PIN, can request a Domain User Account on this web page:

https://www.lsdiv.harvard.edu/hu_auth/account.php

This uses a web form to collect the information we need to create your account. Fill in the requested information and click "Submit Form".

Accounts are usually created within 1 day. We will notify you as soon as the account has been created (please be sure to include your current email address).

Web Hosting

We provide integrated web hosting solutions in Windows or Linux environments using IIS (Windows only) or Apache. Databases include MySQL (with phpMyAdmin), SQL and Oracle. Supported scripting languages are PHP, ASP, ASP.NET and PERL. Contact Brian Gottesman for assistance.